2-BENZOYL-5-METHOXY-1-PHENOL-4-SULFONIC ACID (BENZOPHENONE 4)

SULISOBENZONE

PRODUCT IDENTIFICATION

CAS NO.

4065-45-6

2-BENZOYL-5-METHOXY-1-PHENOL-4-SULFONIC ACID

EINECS NO.

223-772-2

FORMULA

C₁₄H₁₂O₆S

MOL WT.

308.31

H.S. CODE

2914.70

SMILES

TOXICITY

SYNONYMS

Benzophenone 4; 2-羟基-4-甲氧基-5-磺酸二苯酮;

Sulissobenzona; 3-Benzoyl-4-hydroxy-6-methoxybenzenesulfonic acid; 5-Benzoyl- 4-hydroxy-2-methoxybenzenesulfonic acid; Sulsisobenzone; 2-Hydroxy-4- methoxybenzophenone-5-sulfonic acid; 2-Hydroxy-4- methoxybenzophenone- 5-sulphonic acid dihydrate; Sulisobenzone; 2-Benzoyl-5-methoxy-1-phenol-4-sulfonic acid;

CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE

Off white to yellow crystalline powder

MELTING POINT

108 C

BOILING POINT

SPECIFIC GRAVITY

SOLUBILITY IN WATER

soluble

1.2 - 2.2 (10% aq sol.)

VISCOSITY

AUTOIGNITION

REFRACTIVE INDEX

NFPA RATINGS

FLASH POINT

STABILITY

stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS

Benzophenone, an aromatic ketones (diphenyl ketone), is an important compound in organic photochemistry and perfumery as well as in organic synthesis. It is a white crystalline substance with rose-like odor; insolube in water; melting point 49 C; boiling point 305 - 306 C. Benzophenone is used as a constituent of synthetic perfumes and as a starting material for the manufacture of dyes, pesticides and drugs (especially anxiolytic and hypnotic drugs). Benzophenone is used as a photoinitiator of UV-curing applications in inks, adhesive and coatings, optical fiber as well as in printed circuit boards. Photoinitiators are compounds that break down into free radicals upon exposure to ultraviolet radiation. Photoinitiators undergo a unimolecular bond cleavage upon irradiation to yield free radicals (benzoin esters; benzil ketals; alpha-dialkoxy acetophenones; alpha-hydroxy alkylphenones; alpha-amino alkylphosphine; acylphosphine oxides). Another type of photoinitiators undergo a bimolecular reaction where the excited state of the photoinitiator interacts with a second molecule (a coinitiator) to generate free radicals (benzophenones, amines; thioxanthones, titanocenes). Ultraviolet radiation has more energy than visible light, and thus degrade the physical properties such as the appearance of organic substances and plastics. Benzophenones can act as optical filters or deactivate substrate molecules that have been excited by light for the protection polymers and organic substances. They, cosmetic grades, are used as sunscreen agents to reduce skin damage by blocking UV-A, B.

Chemical ingredients for sunscreen are;

p-Aminobenzoic acids

p-Aminobenzoic acid (CAS #: 150-13-0)
p-Aminobenzoic Acid, monoglyceryl Ester (CAS #: 136-44-7)
p-Aminobenzoic Acid, octyl dimethyl Ester (Padimate 0, CAS #: 21245-02-3)
p-Aminobenzoic Acid, ethyl dihydroxypropyl (Roxadimate, CAS #: 58882-17-0)
p-Aminobenzoic Acid, 2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide ester
Octyl Triazone (CAS #: 88122-99-0)
p-Aminobenzoic Acid, PEG-25 (CAS #: 116242-27-4)

Anthranilates

Menthyl anthranilate (CAS #: 134-09-8)

Benzophenones

Benzophenone (CAS #: 119-61-9)
2,4-Dihydroxybenzophenone (Benzophenone-1, CAS #: 131-56-6)
2,2',4,4'-Tetrahydroxybenzophenone (Benzophenone-2, CAS #: 131-55-5)
2-Hydroxy-4-methoxybenzophenone (Benzophenone-3, Oxybenzone, CAS #: 131-57-7)
2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid (Benzophenone-4, Sulisobenzone, CAS #: 4065-45-6
2-Hydroxy-4-methoxybenzophenone-5-sulfonic Acid, Monosodium Salt (Benzophenone-5, CAS #: 6628-37-1)
2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (Benzophenone-6, CAS #: 131-54-4)
5-Chloro-2-hydroxybenzophenone (Benzophenone-7, CAS #: 85-19-8)
2,2'-Dihydroxy-4-methoxybenzophenone (Benzophenone-8, Dioxybenzone, CAS #: 131-53-3)
2,2'-Dihydroxy-4,4'-dimethoxybenzophenone-5,5'-disulfonic Acid Sodium Salt (Benzophenone-9, CAS #: 76656-36-5)
2-Hydroxy-4-methoxy-4'-methyl-benzophenone (Benzophenone-10, Mexenone, CAS #: 1641-17-4)
Bis(2,4-ihydroxyphenyl)Methanone (Benzophenone-11, CAS #: 1341-54-4)
2-Hydroxy-4-(Octyloxy)Benzophenone (Benzophenone-12, Octabenzone, CAS #: 1843-05-6)
2,2'-Dihydroxy-4-methoxybenzophenone (Dioxybenzone, CAS #: 131-53-3)
2-Hydroxy-4-methoxybenzophenone (Oxybenzone, CAS #: 131-57-7)
2-Hydroxy-4-methoxybenzophenone-5-sulphonic Acid (Sulisobenzone, CAS #: 4065-45-6)

Camphors

Benzylidene Camphor Sulfonic Acid (CAS #: 56039-58-8)
3-Benzylidene Camphor (CAS #: 15087-24-8)
Polyacrylamidomethyl Benzylidene Camphor (CAS #: 113783-61-2)
Terephthalylidene Dicamphor Sulfonic Acid (CAS #: 90457-82-2)
3-(4-Methylbenzyliden)Camphor (CAS #: 36861-47-9)
Camphor Benzalkonium Methosulfate (CAS #: 52793-97-2)
Bornelone (CAS #: 2226-11-1)

Cinnamates

Ethyl Cinnamate (CAS #: 103-36-6)
2-Ethoxyethyl-p-methoxycinnamate (Cinoxate, CAS #: 104-28-9)
Isoamyl P-methoxycinnamate (CAS #: 71617-10-2)
Diisopropyl Methyl Cinnamate (CAS #: 32580-71-5)
2-Ethylhexyl Alpha-cyano-beta-phenylcinnamate (Octocrylene, CAS #: 6197-30-4)
Diethanolamine Methoxycinnamate (CAS #: 56265-46-4)
Isopropyl Methoxycinnamate (CAS #: 5466-76-2)
Isoamyl P-methoxycinnamate (CAS #: 71617-10-2)
Glyceryl Octanoate Dimethoxycinnamate
Ethyl Diisopropylcinnamate (CAS #: 32580-72-6)
Ethyl Methoxycinnamate (CAS #: 99880-64-5)
Octyl Methoxycinnamate (CAS #: 5466-77-3)

Dibenzoylmethanes
- Dibenzoylmethane (CAS #: 120-46-7)
- Isopropyl Dibenzoylmethane (Eusolex, CAS #: 63250-25-9)
- 4-tert-Butyl-4'-methoxy-dibenzoylmethane (Avobenzone, CAS #: 70356-09-1)
Salicylates

3,3,5-Trimethylcyclohexyl Salicylate (Homosalate, CAS #: 118-56-9)
Benzyl Salicylate (CAS #: 118-58-1)
Octyl Salicylate (CAS #: 118-60-5)
2-Hydroxyethyl Salicylate (CAS #: 87-28-5)
Menthyl Salicylate (CAS #: 89-46-3)
Isopropylbenzyl Salicylate (CAS #: 94134-93-7)

Imidazoles

Phenylbenzimidazole
Phenylbenzimidazol-5-sulfonic Acid (CAS #: 27503-81-7)
Phenylbenzimidazole Tea Sulfonate (CAS #: 73705-00-7)
Urocanic Acid (4-Imidazoleacrylic Acid, CAS #: 104-98-3)
Ethyl Urocanate (CAS #: 27538-35-8)
Bisymidazylate (CAS #: 180898-37-7)
Sodium Phenylbenzimidazole Sulfonate (CAS #: 5997-53-5)

Others

Petrolatum Jelly (CAS #: 8009-03-8)
Ethyl 2-cyano-3,3-diphenylacrylate (Etocrilene, CAS #: 5232-99-5)
Diurethane Dimethacrylate (CAS #: 103597-45-1)
Drometrizole Trisiloxane (CAS #: 155633-54-8)
Bis(Ethylhexyloxyphenol Methoxyphenol) Triazine (CAS #: 187393-00-6
2-(2-Hydroxy-5-methyl-phenyl)Benzotriazole (Drometrizole, CAS #: 2440-22-4)
Dioctyl Butamido Triazone (CAS #: 154702-15-5)

Inorganic compounds (physical sunscreens)

Titanium dioxide
Zinc oxide

2-Benzoyl-5-methoxy-1-phenol-4-sulfonic acid is used as an UV A and B absorber especially for water soluble formulation is required. It is used as a sunscreen agent in cosmetics, hair days and hair sprays.

SALES SPECIFICATION

APPEARANCE

Off white to yellow crystalline powder

ASSAY

99.5% min

ACIDITY

165 - 175 (KOH mg/g)

K-VALUE

46 min (l/gr-cm, at 285nm)

LOSS ON DRYING

3.0% max

TRANSPORTATION

PACKING

HAZARD CLASS

UN NO.

BENZOPHENONE SERIAL

Number	Chemical name	CAS RN
Benzophenone-1	2,4-Dihydroxybenzophenone	131-56-6
Benzophenone-2	2,2',4,4'-Tetrahydroxybenzophenone	131-55-5
Benzophenone-3	Oxybenzone	131-57-7
Benzophenone-4	Sulisobenzone	4065-45-6
Benzophenone-5	2-Hydroxy-4-methoxybenzophenone-5-sodium sulfonate	6628-37-1
Benzophenone-6	2,2'-Dihydroxy-4,4'-dimethoxybenzophenone	131-54-4
Benzophenone-7	Chlorohydroxy benzophenone	85-19-8
Benzophenone-8	Dioxybenzone	131-53-3
Benzophenone-9	Disodium 2,2'-dihydroxy-4,4'-dimethoxy-5,5'-disulfobenzophenone	3121-60-6
Benzophenone-10	Mexenone	1641-17-4
Benzophenone-11	Bis(2,4-dihydroxyphenyl)methanone	1341-54-4
Benzophenone-12	Octabenzone	1843-05-6

PRICES